Multiple Chemical Sensitivity: Current Concepts

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Evolving concepts of chemical sensitivity.

Chemical sensitivity appears to be an elusive phenomenon. Studies on individual differences in susceptibility may provide glimpses into the range of sensitivity in a population, which can be used for further study. Preliminary evidence in laboratory animals suggests the range of sensitivity to manufactured chemicals may span orders of magnitude. Determining the reasons that underlie individual ...

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Multiple Chemical Sensitivity

OBJECTIVE Systematic bibliography analysis of about the last 17 years on multiple chemical sensitivity (MCS) was carried out in order to detect new diagnostic and epidemiological evidence. The MCS is a complex syndrome that manifests as a result of exposure to a low level of various common contaminants. The etiology, diagnosis, and treatment are still debated among researchers. METHOD Queryin...

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Multiple Chemical Sensitivity: Toxicological and Sensitivity Mechanisms

Cases of multiple chemical sensitivity (MCS) are reported to be initiated by seven classes of chemicals. Each of the seven acts along a specific pathway, indirectly producing increases in NMDA activity in the mammalian body. Members of each of these seven classes have their toxicant responses lowered by NMDA antagonists, showing that the NMDA response is important for the toxic actions of these...

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Olfaction and multiple chemical sensitivity.

In this paper, a description of olfactory anatomy is presented, followed by a brief review of modern procedures for testing olfactory function. Information from the sole study which has quantitatively examined olfactory function in patients with apparent multiple chemical sensitivity (MCS) is presented. In essence, this study suggests that MCS is associated with increased nasal airflow resistan...

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ژورنال

عنوان ژورنال: International Journal of Immunopathology and Pharmacology

سال: 2007

ISSN: 2058-7384,2058-7384

DOI: 10.1177/039463200702001s02